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TOPIC: Mayo Clinic Fistula

Mayo Clinic Fistula 13 Jun 2016 18:43 #7229

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The field, especially the procedures to apply ADRCs, conti ues to advance. This This is a novel way to apply cells to fistula.
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Mayo Clinic Fistula 14 Jun 2016 23:10 #7243

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Great find that confirms the relevance of ADRC in this indication. The Mayo procedure involves culturing which increases by orders of magnitude the complexity and cost of the procedure. The Celution device is ideal for this sort of indication.

We have a number of investigator led trials that confirmed the feasibility and effectiveness of ADRC and fibrin glue (matrix). We have had CE approval for these indications for years which begs the question what have we been doing to monetize this indication.??????? Management chose to dilute the hell out of existing shareholders because they want to "have their cake and eat it too".
One wonders :evil: for whose benefit the poison pill provisions exist. At these SP levels (petty cash) some BB OR BP would normally be expected to launch a takeover. Management will have their cake, and eat it too.

Thankfully the French have seen fit to undertake a trial in this indication. Their approach appears quite novel in using ADRC/SVF plus adipose tissue as a bulking agent/matrix. It would be nice if they had a fibrin arm also, but beggars can't be choosers.


With positive results I do not see why we could not go straight into a pivotal trial in the USA for this indication, much like scleroderma. Given that the patients being treated have an intractable condition and the trial is not blinded I believe that the efficacy of the treatment should be recognizable within 16 weeks even though the trial is for a period of 48 weeks duration. :winky:

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