Wednesday, 19 February 2014 07:47

The One that got away

If there is one thing that MDs and scientists who briefly experiment with fat cells agree upon with their colleagues who devote most of their lives studying these cells than it would be - yes- they seem to improve blood flow nicely. But why that is, has never really been all that clear. When Zuk et al plated the approx. 2% of plastic adherent SVF back in 2001/2 they apparently also did not know, which was evidenced approx. 4 years later in 2006, when UCLA  and Pittsburgh scientists battled in court with the ownership of the invention of the stromal part in SVF at stake. Pittsburgh won that battle, since they could produce a laboratory piece of paper with the handwritten note "Mesenchymal cell?" on it and Judge Consuela Marshall decided to become a free-lance scientist by suggesting that the MSCs must have travelled to the fat from the marrow and just changed properties slightly due to their new environment. Escaping "patent profanity"- patent lawyers call that. Neat story, but nowadays we know better thanks to the monumental work of Dr. Arnold Caplan from 2011- The Mesenchymal Stem Cell- an Injury Drugstore- which you can download at the bottom of this article.

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